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Speed of onset and efficacy of zolmitriptan nasal spray in the acute treatment of migraine: a randomised, double-blind, placebo-controlled, dose-ranging study versus …复制

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BR Charlesworth, AJ Dowson, A Purdy, WJ Becker…
CNS drugs, 2003
Springer
Objective: Zolmitriptan oral tablet is highly effective and well tolerated in the acute treatment of migraine with and without aura in adults. A nasal spray formulation has now been developed. The objective of this study was to compare the efficacy and tolerability of fixed doses of zolmitriptan administered via a nasal spray with placebo and zolmitriptan oral tablet in the acute treatment of migraine. Patients and study design: This was a randomised, double-blind, double-dummy, placebo-controlled, parallel-group, multicentre, dose-ranging …

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