Evaluation of 18F-Rho6G as a Novel PET Tracer for Myocardial Perfusion Imaging in a Swine Ischemia Reperfusion Model.
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S Thorn, D Labaree, N Nabulsi, P Emery, Z Felchner…
2019
jnm.snmjournals.org
235 Objectives: Myocardial perfusion imaging is routinely used for assessment of relative blood flow in the detection of coronary artery disease and for risk-stratification. PET imaging offers intrinsic advantages in spatial resolution and sensitivity. However, currently available FDA approved PET perfusion agents have short half-lives requiring an on-site generator or cyclotron. We sought to evaluate a new perfusion agent based on an 18 F-labeled rhodamine dye (18 F-Rho6G) and to determine the myocardial extraction fraction and …
