期刊论文Aerosol-filling equipment for the preparation of pressurized-pack pharmaceutical formulations复制

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C Sirand, JP Varlet, AJ Hickey
… inhalation aerosol technology …, 2003
books.google.com
Changes to manufacturing processes of propellant-based metered-dose inhalers (pMDIs) due to the transition to hydrofluoroalkane-(HFA-) based formu lations from chlorofluorocarbon-(CFC-) based systems are under way. These changes are proceeding concurrently with reformulation efforts of the pMDI systems themselves. In some cases, this may result in changes to the formulation [1].