Enhancing USP< 825> Compliance in Transarterial Radioembolization Using 90Y Resin Microspheres
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X Nie, K Lemieux, W Denton…
Journal of Nuclear …, 2026
tech.snmjournals.org
USP< 825> mandates 1-h beyond-use date (BUD) for immediate-use radiopharmaceuticals, posing workflow challenges for complex transarterial radioembolization procedures using 90 Y-labeled resin microspheres (90 Y-RM). To enhance compliance and patient safety, our institution transitioned 90 Y-RM dose preparation from an in-house process to a local commercial nuclear pharmacy, enabling a BUD of up to 96 h. We retrospectively reviewed 120 cases of 90 Y-RM preparation and administration. In the old workflow (n= 55), the …
