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Lesion penetration predicts tuberculosis regimen success: a validated translational tool for de-risking late-stage drug development复制

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R Savic, J Ernest, A Bustion, A Patel, J Sarathy, F Kaya…
2025
researchsquare.com
… RZL, and TBD-11 were not available; clinical projections of lesion PK for TBD-11 were done
… -phase clinical trials had similar profiles to BPaL and HPZM.Only three additional regimens …

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