Fluoride and Cardiovascular Diseases: Epidemiologic Investigations and Mechanistic Insights
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J Yu, H Qian, M Wang, Z Zhou, S Sun, S Wan…
… Trace Element Research, 2026
Springer
Fluorine is a trace element that is beneficial to human health. However, long-term and excessive fluoride exposure can damage bone and teeth, as well as the cardiovascular, nervous, and reproductive systems, etc. Since 2001, a growing body of evidences suggests that excessive fluoride exposure is associated with cardiovascular diseases. Although some original studies have focused on this topic, general and narrative reviews are rare. This article summarizes the effects of fluoride on blood pressure/hypertension, vascular sclerosis …
