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Bicyclic 6+ 6 systems: advances in the chemistry of heterocyclic compounds incorporated pyrimido [1, 2-a] pyrimidine skeleton复制

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M Monier, D Abdel-Latif, A El-Mekabaty…
Mini-Reviews in …, 2020
ingentaconnect.com
The present review has highlighted the chemistry of pyrimido [1, 2-a] pyrimidine compounds as one of the most important classes of heterocyclic systems. The main sections include:(1) The synthesis of pyrimido [1, 2-a] pyrimidines,(2) reactivity of the substituents attached to the carbon and nitrogen atoms of the ring and (3) biological applications. A discussion demonstrated that the proposed mechanisms of unexpected synthetic routes were intended. The purpose of this review is to provide an overview of the chemistry of pyrimido [1, 2-a] …

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