Airway mucus plugs on chest computed tomography are associated with exacerbations in chronic obstructive pulmonary disease
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E Wan, A Yen, R Elalami, S Grumley…
American Journal of …, 2025
atsjournals.org
Rationale: Acute exacerbations (AEs) of chronic obstructive pulmonary disease (COPD) are associated with significant morbidity and mortality. Whether mucus plugs are associated with prospective exacerbations has not been examined extensively. Objective: To examine associations between mucus plugs on chest computed tomography (CT) and future moderate-to-severe AEs in two independent cohorts with spirometrically-confirmed COPD. Methods: Mucus plugs were visually identified on baseline chest computed tomography …
