The comparative effects of S-amlodipine versus racemic amlodipine on long-term cardiovascular outcomes in subjects with hypertension: a nationwide population …
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HL Kim, B Lee, S Im
Journal of Cardiovascular Pharmacology, 2022
journals.lww.com
Although S-amlodipine is known to have similar effects in lowering blood pressure and fewer side effects compared to amlodipine (= mixture of S-and R-amlodipine), there are no available data on its impact on long-term cardiovascular prognosis. This retrospective cohort study analyzed claims data from Korean subjects with hypertension treated with either S-amlodipine or amlodipine from 2010 to 2020. Subjects with prior history of cardiovascular disease or stroke were excluded. The composite endpoints of all-cause death, myocardial …
