Inhibition of UVB-induced Inflammatory Response and Regulation of Antimicrobial Peptide LL-37 by Polysaccharide Extracts from Saussurea laniceps.
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MA Wenrui, LIU Junchen, Z Hongyan…
… Food Science & …, 2025
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English In order to study the effects of Saussurea laniceps polysaccharides (SLPs) on the expression of inflammatory factors and antimicrobial peptide LL-37 in UVB-induced keratinocytes, SLPs were extracted by the ethanol thermal reflux method, and SLPs at different concentrations were used to examine the inhibitory effect of COX-2 (a key mediator of inflammatory pathway). A cell model of UVB irradiation-induced inflammation was established to determine the influence of SLPs on prostaglandin E2 (PGE-2), TNF-α and IL …
