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DUSP4 knockdown in BRAF V600E mutant colorectal cancer induces cell cycle arrest and halts tumor growth复制

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B Hopfgartner, M Kriz, D Alpar, Y Westermaier…
bioRxiv, 2026
biorxiv.org
… DUSP4 knock-down induces G1 cell cycle arrest and reduces proliferation in BRAF V600E
-mutant and BRAF … that DUSP4 may have limited efficacy as a monotherapy target in cancer. …

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