Osteoinduction mechanism of calcium phosphate biomaterials in vivo: a review
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L Cheng, T Yu, Z Shi
Journal of biomaterials and tissue …, 2017
ingentaconnect.com
Calcium phosphate (Ca–P) biomaterials, combined with hydroxyapatite (HA), tricalcium phosphate (TCP), biphasic calcium phosphate (BCP) ceramics, etc., can induce ectopic bone formation in non-osseous sites of animals without addition of any osteogenic cells or growth factors, which is defined as osteoinduction. The bone induction phenomenon is a miraculous and extremely complex process. Although tremendous progresses have been achieved, a great demand of discovery of such mechanisms are still urgently required. In this …
