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Conformation matters: siRNAs with antisense strands with 5′-(E)-vinyl-phosphonate-α-l-LNA elicit stronger RNAi-mediated gene silencing than those with 5′-(E)-vinyl-phosphonate-LNA复制

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DOI: 10.1039/d4cc04302b复制

文献链接: https://xlink.rsc.org/?DOI=D4CC04302B复制

其他信息:

出版社: Royal Society of Chemistry (RSC)
作者: Dhrubajyoti Datta; Pawan Kumar; Soham Mandal; Monika Krampert; Martin Egli; Patrick J. Hrdlicka; Muthiah Manoharan

上一篇：Expanding the binding space of argonaute-2: incorporation of either E or Z isomers of 6'-vinylphosphonate at the 5' end of the antisense strand improves RNAi activity

下一篇：Enzymatic Desialylation Enables Reliable Charge Variant Characterization of Highly Glycosylated and Sialylated Fc Fusion Proteins

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