Differences in innate immune response between man and mouse
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DOI:
文献链接: https://pubmed.ncbi.nlm.nih.gov/25404048
其他信息:
PMID: 25404048
作者: Josefin Zschaler; Denise Schlorke; Juergen Arnhold; Josefin Zschaler; Josefin Zschaler; ...
摘要: Mouse strains are frequently used to model human disease states, to test the efficiency of drugs and therapeutic principles. However, the direct translation of murine experimental data to human pathological events often fails due to sufficient differences in the organization of the immune system of both species. Here we give a short overview of the principle differences between mice and humans in defense strategies against pathogens and mechanisms involved in response to pathogenic microorganism...
