Toxicity screening of potential bio-based Polar Aprotic Solvents (PAS)
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SL Waaijers-van der Loop, Z Dang, E Rorije…
Methodology, 2018
rivm.nl
One of the priority areas identified by the Dutch Safe Chemicals Innovation Agenda (SCIA) is solvents [1]. Several polar aprotic solvents (PAS) are of particular concern, being N-methyl pyrolidone (NMP), dimethylacetamide (DMAc) and dimethylformamide (DMF) because of their hazardous toxicological properties and wide dispersive use. All three substances are categorised as substances of very high concern (SVHC) under the European chemicals legislation REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) …
