Erythropoiesis in the human
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DR Higgs, C Babbs, M Kassouf
Hoffbrand's Postgraduate …, 2025
Wiley Online Library
Erythropoiesis is the production of haemoglobin‐containing red blood cells for oxygen delivery to the tissues. Approximately 1–2× 10 12 red cells are produced each day, and this remarkable productivity under stable conditions is also complemented by the capacity for rapid and substantial expansion when required. This chapter describes the developmental origins of primitive and definitive erythropoiesis in the yolk sac, the fetal liver and the bone marrow. Our current understanding of the mechanisms of erythroid lineage specification …
