Crosslinking sodium hyaluronate gel with different ratio of molecular weight for subcutaneous injection: animal experimental study and clinical trials subcutaneous …
DOI:
文献链接: 10.3760/cma.j.issn.1009-4598.2015.03.011
其他信息:
W Ran, X Wang, Y Hu, S Gao, Y Yang…
… Zheng Xing wai ke za …, 2015
europepmc.org
Objective To investigate the biocompatibility and degradation rate of crosslinking sodium hyaluronate gel with different ratio of molecular weight, so as to choose the effective, safe and totally degraded hyaluronate gel for aesthetic injection. Methods (1) Compound colloid was formed by cross-linking the divinyl sulphone and sodium hyaluronate with different molecular weight (4 x 10 (5), 8 x 10 (5), 10 x 10 (5), 12 x 10 (5)).(2) Healthy level KM mice was randomly divided into two groups to receive hyaluronic acid gel or liquid injection. Each …
