H-Terminated Catellani Strategy to Aryl β-Ethanol Enables Collective Total Syntheses of Pyranonaphthoquinone Natural Products
1. 文件大小不能超过300M, 允许上传文档或压缩包等
2. 请确保上传文献的真实性、完整性，不得对原文做任何修改
注: 所有应助的资源仅供学习交流使用, 不得违反相关法律法规
DOI:
文献链接:
其他信息:
W Song, C Zhang, Z Jin, J Shen, W Xu, Y Zhang
Organic Letters, 2026
ACS Publications
We report an ipso-H-terminated variant using inexpensive formate as the terminating reagent. Coupling with diverse epoxides provides complementary access to valuable aryl β-ethanols with high regioselectivity. Integration with oxa-Pictet–Spengler and Ullmann reactions enables a collective total synthesis of pyranonaphthoquinone natural products. This strategy features significantly reduced synthetic steps, improved overall yields, and robust conditions, establishing a modular platform for structurally diverse aryl ethanol …
