The thalidomide experience: review of its effects 50 years later
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ML Martínez-Frías
Medicina clínica, 2011
europepmc.org
This year is the 50 (th) anniversary of the discovery that the drug thalidomide causes birth defects and should therefore be considered as a teratogen. However, despite the existence of several other drugs that are also human teratogens, thalidomide continues to cause concern among health professionals as well as the general population. The objectives of this article are to make a short historical review of the discovery that this drug severely alters the embryo development, the critical period of gestation and the identification of the real …
