Disentangling tryptophan metabolism in inflammatory bowel diseasesIF 23.0SCIEJCR Q1医学1区Top
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C Becker, TE Adolph
Gut, 2023
gut.bmj.com
The concept that the cellular metabolism of immune and tissue-resident cells controls immune responses in and beyond the gut has emerged over the last decades. 1 In the gut mucosa, cell metabolism is shaped by our diet and the commensal microbiota. 2 The essential amino acid tryptophan, which is enriched in animal-based protein derived from, for example, egg, red and white meat, fish and milk, is metabolised by the gut microbiota and host cells generating metabolites with immune-modulatory functions. Microbes metabolise …
