Medium-chain fatty acids and monoglycerides: Nanoarchitectonics-based insights into molecular self-assembly, membrane interactions, and applications
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BK Yoon, JA Jackman
Advances in Colloid and Interface Science, 2025
Elsevier
Medium-chain fatty acids (FAs) and monoglycerides (MGs) with saturated 6-to 12‑carbon long tails are single-chain lipid amphiphiles that demonstrate significant application merits. Key examples include their antimicrobial activity against antibiotic-resistant bacteria and emerging viral threats as well as innovations in oral pharmaceutics and biorenewable chemical production. These diverse functionalities are enabled by FA and MG self-assembly and their interactions with biological membranes. However, an integrated viewpoint …
