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ACE2 and vasoactive peptides: novel players in cardiovascular/renal remodeling and hypertensionACE2 与血管活性肽:心血管/肾脏重塑及高血压中的新角色复制

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E Mendoza-Torres, A Oyarzún…
Therapeutic …, 2015
journals.sagepub.com
The renin–angiotensin system (RAS) is a key component of cardiovascular physiology and homeostasis due to its influence on the regulation of electrolyte balance, blood pressure, vascular tone and cardiovascular remodeling. Deregulation of this system contributes significantly to the pathophysiology of cardiovascular and renal diseases. Numerous studies have generated new perspectives about a noncanonical and protective RAS pathway that counteracts the proliferative and hypertensive effects of the classical angiotensin-converting …

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