Targeting Multiple KRAS Mutations with High-Affinity Macrocyclic Inhibitors: From Discovery to Preclinical Validation
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DOI: https://doi.org/10.1021/acs.jmedchem.6c00127
文献链接: https://pubs.acs.org/doi/10.1021/acs.jmedchem.6c00127
其他信息:
出版社: American Chemical Society (ACS)
作者: Dean P. Phillips; Phil B. Alper; Charles Y. Cho; Dmitry Borkin; Dong Han; Sarah E. Kochanek; Agnes Vidal-Biggart; Ananda Herath; Jitendra Gurjar; Wenshuo Lu; Casey J. N. Mathison; John M. Nelson; Wei Pei; Shanshan Yan; Bao Ngoc Nguyen; Timothy Hoffman; Barun Okram; Truc N. Nguyen; Songchun Jiang; Brian T. Masick; Zhicheng Wang; Victor Nikulin; Hong Yin; Yu Chen; Jose Juarez; Yelena Sarkisova; Yong Jia; Vicki Zhou; Guoxun Liu; Xianzhong Liu; Min Lu; Brandon L. Taylor; Lang Huynh; Yu Wang; Reynand Pacoma; Janine Baaten; Kathryn Topolewski; Clifford Wright; Trish Nguyen; Deborah A. Knee; Qian Liu; Jun Liu; Jie Li; Cyrus Virata; Sergio Briones; Michael DiDonato; Badry Bursulaya; David H. Jones; Darbi Witmer; Carolyn Chu; Hong Jin; Wendy Richmond; Lucas Westling; Thomas Hollenbeck; Ashley Chong; Sally Franey; Todd Groessl; Michael Shapiro; Kathleen Effenberger; Konrad Arroyo; Angela Bretz; Ayako Honda; James Brown; Carina C. Sanchez; William P. Gordon; Jason T. Matzen; Nils Osterman; Simona Cotesta; Saskia M. Brachmann; Rainer Wilcken; Frederic Zecri; Kim S. Beyer; Valentina Molteni; Jacob R. Haling
全文下载地址: https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6c00127
