From cell cycle control to cancer therapy: exploring the role of CDK1 and CDK2 in tumorigenesis
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J Gupta, BI Saeed, AK Bishoyi, AG Alkhathami…
Medical Oncology, 2025
Springer
The cyclin-dependent kinase (CDK) family comprises one of the most common types of serine/threonine kinases responsible for controlling many cellular processes through the action of the dynamics of these enzymes. The CDKs are regulators of cellular processes, ranging from cell cycle progression, an integral step of cellular lifespan involved in its division and growth, to the expression of genes and the transfer of genetic information from DNA to RNA. CDK-related pathology is primarily based on the dysregulation of CDK …
