期刊论文Recombinant tissue factor as substitute for conventional thromboplastin in the prothrombin time test复制

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文献链接: https://pubmed.ncbi.nlm.nih.gov/1615481复制

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PMID: 1615481
作者: A Tripodi; A Arbini; V Chantarangkul; P M Mannucci; A Tripodi; ...
摘要: Relipidated recombinant tissue factor (r-TF) has been assessed in comparison with conventional rabbit brain thromboplastin (Manchester Reagent) for its suitability for measurement of prothrombin time (PT). The International Sensitivity Index (ISI) of r-TF calibrated against the International Reference Preparation BCT/253 (human plain) was found to be 0.96 and 1.12 with instrumental and manual techniques. Our study of plasmas from patients with congenital deficiencies of clotting factors covering...