Longer occupancy of opioid receptors by nalmefene compared to naloxone as measured in vivo by a dual-detector system
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DOI:
文献链接: https://pubmed.ncbi.nlm.nih.gov/9374341
其他信息:
PMID: 9374341
作者: S Kim; H N Wagner Jr; V L Villemagne; P F Kao; R F Dannals; ...
摘要: Surgical procedures usually involve the administration of narcotic drugs as anesthetics or adjuvants. To reverse the effects of anesthesia, opioid antagonists such as naloxone are commonly used. Due to its short lasting effects, patients receiving naloxone must be monitored carefully. Nalmefene, a pure opiate antagonist with a longer duration of action than naloxone, has shown promise in the reversal of opioid anesthesia.
