当前位置：首页 > 文献互助 > 互助详情

YN1548: A novel small-molecule agonist of human glucagon-like peptide-1 receptor for the treatment of type 2 diabetes mellitus and obesity复制

用户lzQQTKAQxKiY 1个月前 89 10 已完结

1. 系统已在2026-08-11 11:47:06对应助文件进行删除

2. 如有需要请重新发布求助信息

注: 所有应助的资源仅供学习交流使用, 不得违反相关法律法规

DOI:复制

文献链接:复制

其他信息:

IG Je, TK Kim, HJ Lee, MY Lee, KM An, JT Park…
European Journal of …, 2025
Elsevier
Type 2 diabetes mellitus (T2DM) and obesity are the major global health concerns. Glucagon-like peptide-1 (GLP-1) receptor agonists are effective incretin-based treatments for T2DM and obesity. The patient compliance of peptide-based GLP-1 receptor agonists is limited due to subcutaneous administration. This study aimed to develop small-molecule GLP-1 receptor agonists that can be administered orally. Pharmacological properties of YN1548 were evaluated using in vitro assays in Chinese hamster ovary (CHO) cells …

上一篇：Chemical synthesis, structural analysis, and decomposition of N-nitroso bile acid conjugates

下一篇：Total Synthesis of (−)-Retigeranic Acid A: A Reductive Skeletal Rearrangement Strategy

互助时间线

2026-08-04 13:08:27 [完结求助]

楼主确认了jodie0105应助的文件是正确的, 求助状态变成 已完结

2026-08-04 11:47:06 [上传文件]

jodie0105上传了文件(pdf 4.11 MB), 求助状态变成 待确认

2026-08-04 11:39:05 [发起求助]

最新发布的求助

The evolving landscape of drug targets 1小时前
Hydrogel microparticles for biomedical applications 2小时前
Dynamic Evolution of Copper Nanowires during CO 2 Reduction Probed by Operando Electrochemical 4D-STEM and X-ray Spectroscopy 3小时前
Enhancing Chinese students’ willingness to communicate (WTC) in EMI classrooms: Do learning motivation and academic self-efficacy matter? 4小时前
Recent Progress on Layered Double Hydroxides and Their Derivatives for Electrocatalytic Water Splitting 4小时前
Promoted OH⁻ Adsorption and Cl⁻ Repulsion Ability of Ce‑Decorated NiFe@CuO for Alkaline Seawater Electrolysis 4小时前
Real-world effectiveness of topical ruxolitinib in non-segmental vitiligo: repigmentation, mental health, and quality-of-life outcomes in an 860-patient multicentre study 7小时前
Cooperative Redox Catalysis of N₂O Decomposition by Short‑Range RhOₓ and CeOₓ Anchored to Co₃O₄ 7小时前
Entropy‑Modified Ceria Regulate Oxygen Vacancy and Manipulate the Electronic Structure of Ruthenium Toward Efficient Hydrogen Evolution 7小时前
Enhanced Hydrogen Spillover and Electronic Coupling in Pt‑CeZrO₄ Enables Efficient and Durable Proton Exchange Membrane Water Electrolysis 7小时前
Single-atom Zr promoter boosts oxygen activation on ceria-supported Pt catalysts 7小时前
First-in-class ACP3 high-affinity ligands isolated from DNA-encoded chemical libraries for the delivery of radionuclides against prostate cancer 8小时前

wispass工作室 Copyright © 蜀ICP备20005939号-4 www.wispass.com