A review of the animal pharmacology of roxatidine acetate
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J Scholtholt, M Bickel, AW Herling
Drugs, 1988
Springer
Summary Roxatidine acetate (TZU 0460/HOE 760)[N-(3-[3-(1-piperidinylmethyl)-phenoxy]-propyl) acetoxyacetamide hydrochloride] is a specific and competitive H2-receptor antagonist with a chemical structure different from those of cimetidine, ranitidine and famotidine. Roxatidine acetate and its main metabolite roxatidine inhibit histamine-induced gastric acid secretion in vitro with a potency greater than that of cimetidine, and in the range of that produced by ranitidine. Gastric acid secretion following stimulation with dibutyryl …
