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Sequential immunotherapy: towards cures for autoimmunityIF 101.8SCIEJCR Q1医学1区Top2024Cited 1复制

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F Ramírez-Valle, JC Maranville, S Roy…
Nature Reviews Drug …, 2024
nature.com
Despite major progress in the treatment of autoimmune diseases in the past two decades, most therapies do not cure disease and can be associated with increased risk of infection through broad suppression of the immune system. However, advances in understanding the causes of autoimmune disease and clinical data from novel therapeutic modalities such as chimeric antigen receptor T cell therapies provide evidence that it may be possible to re-establish immune homeostasis and, potentially, prolong remission or even cure autoimmune …

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