Combination Therapy With Poly D–L Lactic Acid and Autologous Fat Transplantation for Infraorbital Rejuvenation
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LH Earl, SE Yoon, J Wan, JK Song…
Journal of …, 2026
journals.lww.com
Background: Multiple approaches exist for treating infraorbital hollowing, including hyaluronic acid fillers and autologous fat transfer. However, traditional single-modality treatments often present limitations such as the Tyndall effect or unpredictable fat retention rates. Objective: To evaluate the efficacy and safety of a novel combination therapy using poly-D, L-lactic acid (PDLLA) with autologous fat transplantation for infraorbital rejuvenation. Methods: Eight patients (8 females) with varying presentations of infraorbital hollowing were …

