Efficacy and Safety of Medical Interventions for Moderate to Severe Hidradenitis Suppurativa: A Living Systematic Review and Network Meta-Analysis
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A Garg, E Cohn, B Midgette, K Frasier…
JAMA …, 2025
jamanetwork.com
Importance There is limited comparative information on regulatory approved and pipeline treatments in hidradenitis suppurativa (HS). Objective To compare efficacy, safety, and tolerability of treatments for moderate to severe HS. Data Sources MEDLINE, Embase, ClinicalTrials. gov, and Cochrane Central Register of Controlled Trials were searched from inception to June 28, 2024. Study Selection Phase 2 and 3 randomized clinical trials of medical interventions (cytokine inhibitors, small molecule inhibitors, cell inhibitors, and other …

