期刊论文Pathologic changes of spontaneous tumors in Sprague-Dawley and Wistar rats复制

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YN He, SC Zhang, HM Zhang
Zhonghua Bing li xue za zhi …, 2017
europepmc.org
Objective: To investigate the spontaneous neoplastic lesions and their incidences in Sprague-Dawley (SD) and Wistar rats, and to accumulate background data for carcinogenicity studies. Methods: One hundred and eighty SD rats and 240 Wistar rats (4-week old), half in each sex, were used in this study. The rats were housed routinely under specific pathogen-free environment and euthanized after 104 weeks. Histopathological examination was undertaken for all animals including deaths and scheduled euthanasia …