Expanding Conjugate Space of RNAi Therapeutics: Ligand at the 3′ End of the Antisense Strand Achieves Uncompromised In Vivo Potency and Efficacy and Reveals Interactions with the Argonaute-2 PAZ Domain
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DOI: https://doi.org/10.1021/acs.jmedchem.4c02250
文献链接: https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c02250
其他信息:
出版社: American Chemical Society (ACS)
作者: Rajat S. Das; Dhrubajyoti Datta; Christopher R. Brown; Jason A. Gilbert; Amy Chan; Jennifer Willoughby; Swati Gupta; MaryBeth Kim; Rohan Degaonkar; Tim Racie; Li Lei; Mark K. Schlegel; Adam Castoreno; Klaus Charisse; Kallanthottathil G. Rajeev; Martin Egli; Muthiah Manoharan
全文下载地址: https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c02250
