Autosomal dominant polycystic kidney disease: a review
1. 系统已在2025-06-03 11:27:24对应助文件进行删除
2. 如有需要请重新发布求助信息
注: 所有应助的资源仅供学习交流使用, 不得违反相关法律法规
DOI:
文献链接:
其他信息:
FT Chebib, C Hanna, PC Harris, VE Torres, NK Dahl
JAMA, 2025
jamanetwork.com
Importance Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive development of kidney cysts and is the most common inherited kidney disorder worldwide. ADPKD accounts for 5% to 10% of kidney failure in the US and Europe, and its prevalence in the US is 9.3 per 10 000 individuals. Observations ADPKD is typically diagnosed in individuals aged 27 to 42 years and is primarily caused by pathogenic variants in thePKD1 (78%) orPKD2 (15%) genes. Most persons with ADPKD have an affected parent …
