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Drug-metabolism research challenges in the new millennium: individual variability in drug therapy and drug safety复制

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AYH Lu
Drug metabolism and disposition, 1998
Elsevier
One of the most challenging research areas in pharmacology in the new millennium is to understand why individuals respond differently to drug therapy and to what extent that individual variability in disposition is responsible for the observed differences in therapeutic efficacy and adverse reactions. To answer these complex questions, drug-metabolism research will rely on multidisciplinary approaches more than ever to investigate the many components involved in drug metabolism and disposition. Major research challenges …

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