期刊论文Decreased rat rhabdomyosarcoma pulmonary metastases in response to a low methionine diet复制

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文献链接: https://pubmed.ncbi.nlm.nih.gov/3674775复制

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PMID: 3674775
作者: F Breillout; F Hadida; P Echinard-Garin; V Lascaux; M F Poupon; ...
摘要: Many Experimental and human tumor cell lines have been previously described as being dependent upon exogenous methionine for their in vitro proliferation. The rationale of the experiments described herein was to decrease the in vivo growth of malignant tumors by reducing the exogenous methionine available in diets fed to Wistar AG rats bearing the highly metastatic rhabdomyosarcoma, RMS-J1. The methionine content in the diet was reduced either by replacing casein (diet 1) with soybean protein (d...