Hyaluronic acid-based hydrogel loaded with berberine hydrochloride promotes MRSA-infected wound healing
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S Sadeghi, A Katebi, M Ghalamzan, FM Beram…
Talanta, 2026
Elsevier
Antibacterial hydrogels are highly recommended biomaterials for managing chronic wounds. In this study, a berberine hydrochloride-loaded hyaluronic acid/collagen (BH-HA/Col) hydrogel was prepared through an optimization approach. The optimization was performed using HA/Col and EDC/NHS ratios as independent variables while swelling (%) and gel fraction (%) were considered as response parameters. The optimized formulation, which demonstrated optimum swelling (%) and gel fraction (%), was evaluated for its …

