Toward next-generation BNP/NT-proBNP biosensors: multiplexed detection, biofouling control, and digital health integration
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JV Rajendran, A Elahi, P Scully
Heart Failure Reviews, 2026
Springer
In the past five years, rapid progress has been made in biosensor platforms for BNP and NT-proBNP detection. Innovations span fluorescence-based assays (FRET aptasensors, quantum dots, NIR persistent luminescence probes), colorimetric nanozyme-enhanced lateral flow assays, surface-enhanced Raman scattering (SERS) systems and electrochemiluminescence immunoassays. These strategies exploit advances in nanomaterials, photonic engineering, and biointerface design to achieve femtogram-to …

