Development and comparison of iron dextran products
DOI:
文献链接: https://pubmed.ncbi.nlm.nih.gov/9846066
其他信息:
PMID: 9846066
作者: R Lawrence; R Lawrence; R Lawrence
摘要: Iron dextran complex has existed as a parenteral drug formulation for forty years. Two new formulations of this prodrug became available after an older form was withdrawn from distribution in the United States. Molecular weight, lot-to-lot consistency and thermal stability were examined among these three complex formulations using HP-GPC analysis. Also, particle size measurements using transmission electron microscopy and reduction degradation kinetics were determined. In each mode of analysis, ...