Blood pressure effects of the angiotensin II receptor blocker, losartan
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MA Weber, RL Byyny, JH Pratt, EP Faison…
Archives of internal …, 1995
jamanetwork.com
Background: Losartan potassium, the first nonpeptide selective blocker of angiotensin II at the ATI receptor, has been shown to exhibit clinical antihypertensive effects. The aim of the present study was to characterize the efficacy and duration of action of losartan by ambulatory blood pressure monitoring. Methods: The study was performed in nonblack hypertensive patients whose baseline untreated clinical diastolic blood pressures were 95 mm Hg or higher and whose average 24-hour ambulatory diastolic blood pressures were 85 …
