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… Drug Disposition-Pharmacodynamic (TMDD-PD) Modeling of Finasteride and Dutasteride: Impact of Target Binding and Turnover on Non-linear Pharmacokinetics复制

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Y Iwaki, W Lee, Y Aoki, Y Sugiyama
The AAPS Journal, 2025
Springer
… and its turnover. Building upon our previous TMDD modeling of small-molecule drugs, this
analysis illustrates the utility of TMDD-PD modeling in accounting for non-linear PK and PD …

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