Current Status and Perspectives of Novel Radiopharmaceuticals with Heterologous Dual-targeted Functions: 2013–2023
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DOI:
文献链接: https://doi.org/10.1021/acs.jmedchem.4c01608
其他信息:
Z Li, Q Ruan, Y Jiang, Q Wang, G Yin…
Journal of Medicinal …, 2024
ACS Publications
Radiotracers provide molecular-and cellular-level information in a noninvasive manner and have become important tools for precision medicine. In particular, the successful clinical application of radioligand therapeutic (RLT) has further strengthened the role of nuclear medicine in clinical treatment. The complicated microenvironment of the lesion has rendered traditional single-targeted radiopharmaceuticals incapable of fully meeting the requirements. The design and development of dual-targeted and multitargeted radiopharmaceuticals have …