Molecular Mechanisms of Melanin Transfer and Processing by Keratinocytes
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HAF Moreiras
2019
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The skin protects the human body against external aggressions, such as ultraviolet radiation (UVR) and microbial infections. Melanocytes and keratinocytes are the cell types most present in the skin epidermis and are essential to sustain skin pigmentation. Melanocytes synthesize the pigment melanin and are present at the basal layer of the epidermis. Keratinocytes are present in all the layers and are the final recipients of melanin, where it accumulates above the nuclei. Melanin sustains skin pigmentation and protects skin cells …
