The Multifaceted Role of Angiopoietin-Like Proteins in Coronary Heart Disease: From Molecular Mechanisms to Clinical Translation
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J Tan, J Gu
Journal of Cardiovascular Pharmacology, 2022
journals.lww.com
Cardiovascular disease (CVD) remains a leading cause of global disease burden and mortality. According to the Global Burden of Disease (GBD) report, CVD deaths worldwide reached 19.2 million in 2023, representing a 47% increase from 13.1 million in 1990. The number of CVD cases rose from 311 million in 1990 to 626 million in 2023 [1]. Coronary heart disease (CHD) is a major cause of CVD mortality, characterized by atherosclerotic narrowing or even occlusion of the coronary arteries, leading to myocardial ischemia …

