Looking beyond silybin: the importance of other silymarin flavonolignans
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M Selc, A Babelova
Frontiers in Pharmacology, 2025
frontiersin.org
Silymarin, an extract from the seeds of milk thistle (Silybum marianum), has been widely studied and used for its hepatoprotective and pharmacological properties. For decades, both experimental and clinical research has been predominantly focused on a single component, silybin, while other related flavonolignans, such as silychristin, isosilybins, silydianin, dehydrosilybin, and the flavonoid taxifolin, have been understudied. However, these less known components may possess unique or even superior pharmacological activities …
