Detection of “smoke powder” etomidate and its metabolite etomidate acid in blood and urine by UHPLC–MS-MS: application in authentic cases
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Z Liying, Z Junbo, X Wanting, X Ping…
Journal of Analytical …, 2024
academic.oup.com
Recently, etomidate has been widely used as an alternative in illicit drug market. It is usually added to regular cigarette tobacco (commonly known as “cigarette powder”) or mixed in e-reload-alertcigarette oil sold through the Internet, retail stores, or entertainment outlets and other reload-alertchannels. An ultra-high performance liquid chromatography tandem mass spectrometry reload-alertmethod was developed to quantify etomidate and etomidate acid in human blood and urine. reload-alertThe limit of detection (LOD) of etomidate and etomidate acid in blood is 0.5 and 2 ng/mL …reload-alert
