期刊论文Study of the Relation between the Shape of Lacosamide Crystals and the Composition of Crystallization Medium复制

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S Allegaert
2016
cora.ucc.ie
Crystallization is the critical process used by pharmaceutical industries to achieve the desired size, size distribution, shape and polymorphism of a product material. Control of these properties presents a major challenge since they influence considerably downstream processing factors. Experimental work aimed at finding ways to control the crystal shape of Lacosamide, an active pharmaceutical ingredient developed by UCB Pharma, during crystallization was carried out. It was found that the crystal lattice displayed a very strong …