Improved antihypertensive efficacy of the felodipine-metoprolol extended-release tablet compared with each drug alone
DOI:
文献链接: https://pubmed.ncbi.nlm.nih.gov/8173689
其他信息:
PMID: 8173689
作者: B Dahlöf; L Jönsson; O Borgholst; G Ekblad; C Engstrand; ...
摘要: In this double-blind, randomised, three-way crossover (latin square design), multicentre study, the aim was to compare the efficacy and tolerability of the fixed combination of felodipine and metoprolol with the individual components as monotherapy. A total of 58 patients with supine diastolic blood pressure of 100-115 mmHg were treated with (1) a fixed combination of felodipine plus metoprolol 5/50-10/100 mg (FM), (2) felodipine 5-10 mg (F) or (3) metoprolol 50-100 mg (M), for 12 weeks each. Al...
