Clinically translatable ultrasound localization microscopy reveals cerebrovascular remodelling and prognosis in patients with traumatic brain injury
DOI:
文献链接: https://doi.org/10.1038/s41551-026-01714-7
其他信息:
M Li, W Wang, Z Su, J Wu, Y Yang, L Wang…
Nature Biomedical …, 2026
nature.com
Cerebral microcirculation critically determines tissue viability and recovery in neurocritical disorders, yet bedside assessment remains unavailable, forcing intuition-based clinical decisions. Here, in this prospective observational study of 20 patients with traumatic brain injury following decompressive craniectomy, we show that ultrasound localization microscopy (ULM) enables bedside cerebral microvascular assessment in neurocritical care. Conventional ULM requires ultrafast imaging, limiting clinical translation; here we …
