Comparison study of the effects of cationic liposomes on delivery across 3D skin tissue and whitening effects in pigmented 3D skin
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MS Lee, JW Lee, SJ Kim…
Macromolecular …, 2021
Wiley Online Library
Charged phospholipids are employed to formulate liposomes with different surface charges to enhance the permeation of active ingredients through epidermal layers. Although 3D skin tissue is widely employed as an alternative to permeation studies using animal skin, only a small number of studies have compared the difference between these skin models. Liposomal delivery strategies are investigated herein, through 3D skin tissue based on their surface charges. Cationic, anionic, and neutral liposomes are formulated and their size, zeta …
